Johannes von Lintig Selected Research

Vitamin A Deficiency

6/2023	Vitamin A deficiency compromises the barrier function of the retinal pigment epithelium.
6/2022	Diabetes Aggravates Photoreceptor Pathologies in a Mouse Model for Ocular Vitamin A Deficiency.
1/2020	Expression and Characterization of Mammalian Carotenoid Cleavage Dioxygenases.
11/2013	Two carotenoid oxygenases contribute to mammalian provitamin A metabolism.
3/2013	Genetics and diet regulate vitamin A production via the homeobox transcription factor ISX.
7/2012	Lecithin:retinol acyltransferase is critical for cellular uptake of vitamin A from serum retinol-binding protein.
11/2007	CMO1 deficiency abolishes vitamin A production from beta-carotene and alters lipid metabolism in mice.
1/2007	Conversion of beta-carotene to retinal pigment.
11/2006	The Drosophila class B scavenger receptor NinaD-I is a cell surface receptor mediating carotenoid transport for visual chromophore synthesis.

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Johannes von Lintig Research Topics

Disease

9	Vitamin A Deficiency 06/2023 - 11/2006
5	Retinal Degeneration 01/2022 - 01/2010
3	Chronic Disease (Chronic Diseases) 01/2023 - 11/2007
3	Inflammation (Inflammations) 10/2020 - 12/2014
3	Carcinogenesis 12/2014 - 08/2010
2	Neoplasms (Cancer) 12/2017 - 08/2013
2	Anophthalmia with pulmonary hypoplasia 08/2015 - 03/2008
2	Fatty Liver 02/2015 - 11/2007
2	Microphthalmos 03/2008 - 01/2005
1	Vision Disorders (Hemeralopia) 02/2024
1	Lung Injury 02/2023
1	Lung Diseases (Lung Disease) 02/2023
1	Atherosclerosis 11/2020
1	Non-alcoholic Fatty Liver Disease 01/2018
1	Macular Degeneration (Age-Related Maculopathy) 12/2017
1	Craniofacial Abnormalities 04/2017
1	Brachydactyly 04/2017
1	Diabetic Retinopathy (Retinopathy, Diabetic) 08/2015
1	Type 2 Diabetes Mellitus (MODY) 08/2015
1	Hypercholesterolemia 02/2015
1	Hepatocellular Carcinoma (Hepatoma) 12/2014
1	Breast Neoplasms (Breast Cancer) 08/2013
1	Anemia 08/2012
1	Leber Congenital Amaurosis 11/2011
1	Mitochondrial Diseases (Mitochondrial Disease) 03/2011
1	Lung Neoplasms (Lung Cancer) 08/2010
1	Dyslipidemias (Dyslipidemia) 06/2010
1	Pinta 01/2010
1	Metabolic Diseases (Metabolic Disease) 09/2009
1	Atrophy 04/2009
1	Retinal Dystrophies 01/2008
1	Photophobia (Light Sensitivity) 08/2005
1	Hypopigmentation (Hypomelanosis) 08/2005

Drug/Important Bio-Agent (IBA)

13	Carotenoids (Carotene)IBA 02/2023 - 11/2006
7	Vitamin A (Retinol)FDA LinkGeneric 11/2020 - 01/2005
6	RetinoidsIBA 02/2024 - 01/2005
6	Retinaldehyde (Retinal)IBA 01/2022 - 08/2005
4	LipidsIBA 11/2020 - 11/2007
4	EnzymesIBA 01/2018 - 01/2005
3	Proteins (Proteins, Gene)FDA Link 06/2023 - 02/2015
3	OpsinsIBA 01/2022 - 08/2005
3	CholesterolIBA 11/2020 - 06/2010
3	Fatty Acids (Saturated Fatty Acids)IBA 02/2015 - 11/2007
2	SmokeIBA 02/2023 - 08/2010
2	OxygenasesIBA 11/2020 - 10/2020
2	LycopeneIBA 01/2018 - 12/2014
2	Sirtuin 1IBA 01/2018 - 02/2015
2	Retinol-Binding Proteins (Retinoid Binding Proteins)IBA 01/2010 - 01/2007
2	Retinal Pigments (Pigments, Visual)IBA 01/2010 - 01/2007
2	beta Carotene (Betacarotene)FDA Link 09/2009 - 01/2007
1	CryptoxanthinsIBA 02/2023
1	ProvitaminsIBA 02/2023
1	Streptozocin (Streptozotocin)FDA Link 06/2022
1	astaxanthine (astaxanthin)IBA 10/2020
1	AdiponectinIBA 01/2018
1	PowdersIBA 01/2018
1	Phosphotransferases (Kinase)IBA 12/2017
1	Mitogen-Activated Protein Kinase 3IBA 12/2017
1	retinylamineIBA 08/2015
1	ATP-Binding Cassette Transporters (ABC Transporters)IBA 02/2015
1	Coenzyme A (CoA)IBA 02/2015
1	stearoyl-coenzyme A (stearoyl-CoA)IBA 02/2015
1	Cytochrome P-450 Enzyme System (Cytochrome P450)IBA 02/2015
1	Acetyl-CoA CarboxylaseIBA 02/2015
1	AMP-Activated Protein KinasesIBA 02/2015
1	apo-10'-lycopenoic acidIBA 12/2014
1	CarcinogensIBA 12/2014
1	ErbB Receptors (EGF Receptor)IBA 08/2013
1	Anticarcinogenic AgentsIBA 08/2013
1	Fatty Acid-Binding ProteinsIBA 08/2013
1	EstersIBA 07/2012
1	9-cis-retinalIBA 11/2011
1	Superoxide DismutaseIBA 03/2011
1	Adenosine Diphosphate (ADP)IBA 03/2011
1	Tocopherols (Tocopherol)IBA 06/2010
1	Oxidoreductases (Dehydrogenase)IBA 01/2010
1	Rhodopsin (Visual Purple)IBA 01/2010
1	Cone OpsinsIBA 04/2009
1	MorpholinosIBA 03/2008

Therapy/Procedure

2	Therapeutics 12/2017 - 01/2007